(R)-Praziquantel D11

Modify Date: 2024-01-22 10:37:48

(R)-Praziquantel D11 structure	Common Name	(R)-Praziquantel D11
	CAS Number	1399880-38-6	Molecular Weight	323.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₃D₁₁N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (R)-Praziquantel D11

(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer[1].

Name	(R)-Praziquantel D11

Description	(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT2B Receptor Antischistosomal
In Vitro	(R)-Praziquantel ((R)-PZQ) is a G-protein-coupled receptor ligand. (R)-Praziquantel modulation of serotoninergic signaling occurs over a concentration range sufficient to regulate vascular tone of the mesenteric blood vessels where the adult parasites reside within their host. The important anthelmintic is supported by a broad, cross species polypharmacology with (R)-Praziquantel modulating signaling events in both host and parasite[1].
References	[1]. Chan JD, et al. The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. Nat Commun. 2017 Dec 5;8(1):1910.

Molecular Formula	C₁₉H₁₃D₁₁N₂O₂
Molecular Weight	323.47

(R)-Praziquantel D11

Use of (R)-Praziquantel D11

Names

(R)-Praziquantel D11 Biological Activity

Chemical & Physical Properties