2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine

Modify Date: 2024-01-31 19:05:25

2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine structure	Common Name	2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine
	CAS Number	139878-36-7	Molecular Weight	474.71
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₃₉FN₂O₅Si₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine

2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine

Description	2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₂₁H₃₉FN₂O₅Si₂
Molecular Weight	474.71
InChIKey	NLTNXZUKPKJZQK-VDHUWJSZSA-N
SMILES	CC(C)(C)[Si](C)(C)OCC1OC(n2ccc(=O)[nH]c2=O)C(F)C1O[Si](C)(C)C(C)(C)C

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2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine

Use of 2’-Deoxy-2’-fluoro-3’,5’-bis-O-TBDMS-uridine

Names

Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.