VU0455691

Modify Date: 2024-01-02 18:24:43

Use of VU0455691

VU0455691 is a potent, selective orthosteric M1 mAChR antagonist (pIC50=6.64; IC50=0.23 µM for hM1)[1].

Name	[Hexahydro-5-(4-pyridinyl)pyrrolo[3,4-c]pyrrol-2(1H)-yl][1-(5-isoquinolinylsulfonyl)-3-azetidinyl]-methanone

Description	VU0455691 is a potent, selective orthosteric M1 mAChR antagonist (pIC50=6.64; IC50=0.23 µM for hM1)[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> mAChR
References	[1]. Melancon BJ, et al. Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012. Bioorg Med Chem Lett. 2012;22(15):5035-5040.

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: [Hexahydro-5-(4-pyridinyl)pyrrolo[3,4-c]pyrrol-2(1H)-yl][1-(5-isoquinolinylsulfonyl)-3-azetidinyl]-Methanone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3