ZM 241385
ZM 241385 structure
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Common Name | ZM 241385 | ||
|---|---|---|---|---|
| CAS Number | 139180-30-6 | Molecular Weight | 337.336 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C16H15N7O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of ZM 241385ZM 241385 is a selective and high affinity A2A adenosine receptor antagonist. |
| Name | 7-amino-2-(furan-2-yl)-5-[2-(4-hydroxyphenyl)ethyl]amino-[1,2,4]triazolo[1,5-a][1,3,5]triazine |
|---|---|
| Synonym | More Synonyms |
| Description | ZM 241385 is a selective and high affinity A2A adenosine receptor antagonist. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C16H15N7O2 |
| Molecular Weight | 337.336 |
| Exact Mass | 337.128723 |
| PSA | 127.39000 |
| LogP | 0.89 |
| Index of Refraction | 1.791 |
| InChIKey | PWTBZOIUWZOPFT-UHFFFAOYSA-N |
| SMILES | Nc1nc(NCCc2ccc(O)cc2)nc2nc(-c3ccco3)nn12 |
| Storage condition | -20℃ |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| RIDADR | UN 2811 6.1 / PGIII |
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Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish.
Zebrafish 12(2) , 127-36, (2015) Adenosine is a well-known endogenous modulator of neuronal excitability with anticonvulsant properties. Thus, the modulation exerted by adenosine might be an effective tool to control seizures. In thi... |
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Constitutive phospholipid scramblase activity of a G protein-coupled receptor.
Nat. Commun. 5 , 5115, (2014) Opsin, the rhodopsin apoprotein, was recently shown to be an ATP-independent flippase (or scramblase) that equilibrates phospholipids across photoreceptor disc membranes in mammalian retina, a process... |
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Positive allosteric modulation of the adenosine A2a receptor attenuates inflammation.
J. Inflamm. (Lond.) 11(1) , 37, (2014) Adenosine is produced at high levels at inflamed sites as a by-product of cellular activation and breakdown. Adenosine mediates its anti-inflammatory activity primarily through the adenosine A2a recep... |
| 4-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol |
| ZM241385 |
| 4-(2-{[7-amino-2-(furan-2-yl)[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol |
| 4-(2-{[7-Amino-2-(2-furyl)[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol |
| Phenol, 4-[2-[[7-amino-2-(2-furanyl)[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]ethyl]- |
| 4-(2-(7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)ethyl)phenol |