ZM 241385

Modify Date: 2024-01-02 16:26:17

ZM 241385 Structure
ZM 241385 structure
Common Name ZM 241385
CAS Number 139180-30-6 Molecular Weight 337.336
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C16H15N7O2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of ZM 241385


ZM 241385 is a selective and high affinity A2A adenosine receptor antagonist.

 Names

Name 7-amino-2-(furan-2-yl)-5-[2-(4-hydroxyphenyl)ethyl]amino-[1,2,4]triazolo[1,5-a][1,3,5]triazine
Synonym More Synonyms

 ZM 241385 Biological Activity

Description ZM 241385 is a selective and high affinity A2A adenosine receptor antagonist.
Related Catalog
References

[1]. Poucher SM, et al. The in vitro pharmacology of ZM 241385, a potent, non-xanthine A2a selective adenosine receptor antagonist. Br J Pharmacol. 1995 Jul;115(6):1096-102.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C16H15N7O2
Molecular Weight 337.336
Exact Mass 337.128723
PSA 127.39000
LogP 0.89
Index of Refraction 1.791
Storage condition -20℃

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
RIDADR UN 2811 6.1 / PGIII

 Articles8

More Articles
Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish.

Zebrafish 12(2) , 127-36, (2015)

Adenosine is a well-known endogenous modulator of neuronal excitability with anticonvulsant properties. Thus, the modulation exerted by adenosine might be an effective tool to control seizures. In thi...

Constitutive phospholipid scramblase activity of a G protein-coupled receptor.

Nat. Commun. 5 , 5115, (2014)

Opsin, the rhodopsin apoprotein, was recently shown to be an ATP-independent flippase (or scramblase) that equilibrates phospholipids across photoreceptor disc membranes in mammalian retina, a process...

Positive allosteric modulation of the adenosine A2a receptor attenuates inflammation.

J. Inflamm. (Lond.) 11(1) , 37, (2014)

Adenosine is produced at high levels at inflamed sites as a by-product of cellular activation and breakdown. Adenosine mediates its anti-inflammatory activity primarily through the adenosine A2a recep...

 Synonyms

4-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol
ZM241385
4-(2-{[7-amino-2-(furan-2-yl)[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol
4-(2-{[7-Amino-2-(2-furyl)[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol
Phenol, 4-[2-[[7-amino-2-(2-furanyl)[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]ethyl]-
4-(2-(7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)ethyl)phenol
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: ZM241385
  • Price: $500.0/100mg $900.0/250mg $1700.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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Price: $66/10mM*1mLinDMSO

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