Pomolic acid

Modify Date: 2025-08-25 11:13:59

Pomolic acid structure	Common Name	Pomolic acid
	CAS Number	13849-91-7	Molecular Weight	472.700
	Density	1.1±0.1 g/cm3	Boiling Point	586.2±50.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₄₈O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	322.4±26.6 °C

Use of Pomolic acid

Randialic acid A (Pomolic acid) is a pentacyclic triterpene isolated from Euscaphis japonica (Tunb.). Randialic acid A (Pomolic acid) inhibits tumor cells growth and induces cell apoptosis. Randialic acid A (Pomolic acid) has a potential for the treatment of prostate cancer (PC)[2].

Name	pomolic acid
Synonym	More Synonyms

Description	Randialic acid A (Pomolic acid) is a pentacyclic triterpene isolated from Euscaphis japonica (Tunb.). Randialic acid A (Pomolic acid) inhibits tumor cells growth and induces cell apoptosis. Randialic acid A (Pomolic acid) has a potential for the treatment of prostate cancer (PC)[2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
Target	IC50: apoptosis[1]
In Vitro	Randialic acid A (Pomolic acid) induces apoptosis of GBM cells as demonstrated by DNA fragmentation. Pomolic acid-induced apoptosis is dependent on reactive oxygen species (ROS) production. It also induces uncoupling of mitochondria membrane potential and activation of caspase-3 and -9[2].
References	[1]. Guimarães LPTP, et al. Pomolic acid induces apoptosis and inhibits multidrug resistance protein MRP1 and migration in glioblastoma cells.Oncol Rep. 2017 Oct;38(4):2525-2534. [2]. Park JH, et al.Pomolic Acid Ameliorates Fibroblast Activation and Renal Interstitial Fibrosis through Inhibition of SMAD-STAT Signaling Pathways.Molecules. 2018 Sep 3;23(9). pii: E2236.

Density	1.1±0.1 g/cm3
Boiling Point	586.2±50.0 °C at 760 mmHg
Molecular Formula	C₃₀H₄₈O₄
Molecular Weight	472.700
Flash Point	322.4±26.6 °C
Exact Mass	472.355255
PSA	76.66000
LogP	7.40
Vapour Pressure	0.0±3.7 mmHg at 25°C
Index of Refraction	1.568
InChIKey	ZZTYPLSBNNGEIS-OPAXANQDSA-N
SMILES	CC1CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1(C)O

Hazard Codes	Xi

Benthamic acid

3β,19-Dihydroxy-5α-urs-12-en-28-oic acid

Urs-12-en-28-oic acid, 3,19-dihydroxy-, (3β)-

(3β)-3,19-Dihydroxyurs-12-en-28-oic acid

Randialic acid A

3β,19α-Dihydroxyurs-12-ene-28-oic acid

3β,19-Dihydroxyurs-12-en-28-oic acid

(1R,2R,4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-1,10-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid

Serazide