LY3027788
Modify Date: 2025-10-04 18:34:48
LY3027788 structure
|
Common Name | LY3027788 | ||
|---|---|---|---|---|
| CAS Number | 1377615-76-3 | Molecular Weight | 591.576 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H31F2NO11S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LY3027788A orally active prodrug of LY3020371, which is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, respectively; augments the antidepressant-like effects of fluoxetine or citalopram without altering plasma or brain levels of these compounds. |
| Name | LY3027788 |
|---|
| Description | A orally active prodrug of LY3020371, which is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, respectively; augments the antidepressant-like effects of fluoxetine or citalopram without altering plasma or brain levels of these compounds. |
|---|---|
| References | References 1. Witkin JM, et al. J Pharmacol Exp Ther. 2017 Apr;361(1):68-86. View Related Products by Target mGluR |
| Molecular Formula | C25H31F2NO11S |
|---|---|
| Molecular Weight | 591.576 |