YW3-56

Modify Date: 2024-01-06 18:26:09

YW3-56 structure	Common Name	YW3-56
	CAS Number	1374311-17-7	Molecular Weight	494.03
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₂ClN₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of YW3-56

YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.

Name	YW3-56

Description	YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.
Related Catalog	Signaling Pathways >> Epigenetics >> Protein Arginine Deiminase Research Areas >> Cancer
Target	IC50: 1-5 μM (PAD4)[1].
In Vitro	Compared with Cl-amidine, YW3-56 shows >60-fold increase in cell growth inhibition efficacy (IC50 about 2.5 μM) but only 5-fold increase in PAD4 inhibition (IC sub>50 about 1-5 μM). At 2-4 μM concentrations, YW3-56 displays mainly cytostatic effects by slowing cell division, whereas at higher concentrations, it exerts cytotoxic effects by altering cell morphology and killing cells[1].
References	[1]. Wang Y, et al. Anticancer peptidylarginine deiminase (PAD) inhibitors regulate the autophagy flux and t he mammalian target of rapamycin complex 1 activity. J Biol Chem. 2012 Jul 27;287(31):25941-53.

Molecular Formula	C₂₇H₃₂ClN₅O₂
Molecular Weight	494.03

DC Chemicals Limited
China
Product Name: YW3-56
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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