1374311-17-7
1374311-17-7 structure
- Name: YW3-56
- Chemical Name: YW3-56
- CAS Number: 1374311-17-7
- Molecular Formula: C27H32ClN5O2
- Molecular Weight: 494.03
- Catalog: Research Areas Cancer
- Create Date: 2019-02-14 00:01:25
- Modify Date: 2025-08-25 16:20:16
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YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.
| Name | YW3-56 |
|---|
| Description | YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1-5 μM (PAD4)[1]. |
| In Vitro | Compared with Cl-amidine, YW3-56 shows >60-fold increase in cell growth inhibition efficacy (IC50 about 2.5 μM) but only 5-fold increase in PAD4 inhibition (IC sub>50 about 1-5 μM). At 2-4 μM concentrations, YW3-56 displays mainly cytostatic effects by slowing cell division, whereas at higher concentrations, it exerts cytotoxic effects by altering cell morphology and killing cells[1]. |
| References |
| Molecular Formula | C27H32ClN5O2 |
|---|---|
| Molecular Weight | 494.03 |