Timosaponin BII structure
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Common Name | Timosaponin BII | ||
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CAS Number | 136656-07-0 | Molecular Weight | 921.073 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | 1033.6±65.0 °C at 760 mmHg | |
Molecular Formula | C45H76O19 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 578.9±34.3 °C |
Use of Timosaponin BIITimosaponin BII is an antioxidant and an anti-inflammatory agent. |
Name | Timosaponin B II |
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Synonym | More Synonyms |
Description | Timosaponin BII is an antioxidant and an anti-inflammatory agent. |
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Related Catalog | |
In Vitro | Timosaponin BII is a steroidal glycoside separated from Zhi Mu, is found to have the inhibitory activity against the proliferation of HL-60 (leukemic), Hela (cervix), HepG2 and Bel-7402 (liver), HT-29 (colon), and MDA-MB-468 (breast) human carcinoma cell lines with an IC50 value of 15.5 μg/mL in the HL-60 cells[1]. |
In Vivo | Rat retinas in model group and vehicle control group manifest an apparent up-regulation of BACE1 expression. Meanwhile, the level of malonaldehyde (MDA), Aβ1-40 and β-CTF are increased. However, when comparing with the vehicle control group, the retinas in Timosaponin-BII treated group showed significantly less BACE1 and accumulated less Aβ1-40 or β-CTF. It also showed significantly decreased level of MDA and prolonged partial thromboplastin time[2]. |
References |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 1033.6±65.0 °C at 760 mmHg |
Molecular Formula | C45H76O19 |
Molecular Weight | 921.073 |
Flash Point | 578.9±34.3 °C |
Exact Mass | 920.498108 |
PSA | 307.37000 |
LogP | 0.34 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.627 |
(3β,5β,25S)-26-(β-D-Glucopyranosyloxy)-22-hydroxyfurostan-3-yl 2-O-β-D-glucopyranosyl-β-D-galactopyranoside |
Timosaponinb-II |
β-D-Galactopyranoside, (3β,5β,25S)-26-(β-D-glucopyranosyloxy)-22-hydroxyfurostan-3-yl 2-O-β-D-glucopyranosyl- |
N1929 |
Timosaponin B2 |