142759-74-8

142759-74-8 structure

Name: Anemarsaponin BIII
Chemical Name: pseudoprototimosaponin AIII
CAS Number: 142759-74-8
Molecular Formula: C₄₅H₇₄O₁₈
Molecular Weight: 903.058
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-03-23 08:00:00
Modify Date: 2024-01-03 05:33:32
Timosaponin B III is a major bioactive steroidal saponin isolated from Anemarrhena asphodeloides Bge, and exhibits anti-inflammatory, anti-platelet aggregative and anti-depressive effects[1][2][3].

Name	pseudoprototimosaponin AIII
Synonyms	β-D-Galactopyranoside, (3β,5β,25S)-26-(β-D-glucopyranosyloxy)furost-20(22)-en-3-yl 2-O-β-D-glucopyranosyl- (3β,5β,25S)-26-(β-D-Glucopyranosyloxy)furost-20(22)-en-3-yl 2-O-β-D-glucopyranosyl-β-D-galactopyranoside anemarrhenasaponin IV timosaponin B-III timosaponin B timosaponin BIII timosaponin B III anemarsaponin BIII

Description	Timosaponin B III is a major bioactive steroidal saponin isolated from Anemarrhena asphodeloides Bge, and exhibits anti-inflammatory, anti-platelet aggregative and anti-depressive effects[1][2][3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Zhang XL, et al. Timosaponin B-III exhibits antidepressive activity in a mouse model of postpartum depression by the regulation of inflammatory cytokines, BNDF signaling and synaptic plasticity. Exp Ther Med. 2017 Oct;14(4):3856-3861. [2]. Zhao YF, et al. New transformation pathway and cytotoxic derivatives from the acid hydrolysis of timosaponin B III. Nat Prod Res. 2018 Nov 20:1-7. [3]. Kang LP, et al. Steroidal glycosides from the rhizomes of Anemarrhena asphodeloides and their antiplateletaggregation activity. Planta Med. 2012 Apr;78(6):611-6.