21-Desacetyl Deflazacort
21-Desacetyl Deflazacort structure
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Common Name | 21-Desacetyl Deflazacort | ||
|---|---|---|---|---|
| CAS Number | 13649-57-5 | Molecular Weight | 399.48 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 585.0±50.0 °C at 760 mmHg | |
| Molecular Formula | C23H29NO5 | Melting Point | 228-230 °C | |
| MSDS | N/A | Flash Point | 307.6±30.1 °C | |
Use of 21-Desacetyl Deflazacort21-Desacetyldeflazacort (21-desDFZ) is the active metabolite of Deflazacort (HY-13609). Deflazacort is an anti-inflammatory and immunosuppressant. Deflazacort is an inactive pro-drug which can be rapidly converted by esterases to the active metabolite 21-desacetyldeflazacort after oral administration[1]. |
| Name | 21-Desacetyl Deflazacort |
|---|---|
| Synonym | More Synonyms |
| Description | 21-Desacetyldeflazacort (21-desDFZ) is the active metabolite of Deflazacort (HY-13609). Deflazacort is an anti-inflammatory and immunosuppressant. Deflazacort is an inactive pro-drug which can be rapidly converted by esterases to the active metabolite 21-desacetyldeflazacort after oral administration[1]. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 585.0±50.0 °C at 760 mmHg |
| Melting Point | 228-230 °C |
| Molecular Formula | C23H29NO5 |
| Molecular Weight | 399.48 |
| Flash Point | 307.6±30.1 °C |
| Exact Mass | 399.204559 |
| PSA | 96.19000 |
| LogP | 0.90 |
| Vapour Pressure | 0.0±3.7 mmHg at 25°C |
| Index of Refraction | 1.690 |
| InChIKey | KENSGCYKTRNIST-RVUAFKSESA-N |
| SMILES | CC1=NC2(C(=O)CO)C(CC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC32C)O1 |
| Storage condition | 2-8°C |
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21-Desacetyl De... CAS#:13649-57-5 |
| Literature: Steroids, , vol. 13, p. 383 - 397 |
|
~%
21-Desacetyl De... CAS#:13649-57-5 |
| Literature: Steroids, , vol. 13, p. 383 - 397 |
|
~%
21-Desacetyl De... CAS#:13649-57-5 |
| Literature: Steroids, , vol. 13, p. 383 - 397 |
|
~%
21-Desacetyl De... CAS#:13649-57-5 |
| Literature: Steroids, , vol. 13, p. 383 - 397 |
|
~%
21-Desacetyl De... CAS#:13649-57-5 |
| Literature: Steroids, , vol. 13, p. 383 - 397 |
|
~%
21-Desacetyl De... CAS#:13649-57-5 |
| Literature: Steroids, , vol. 13, p. 383 - 397 |
|
~%
21-Desacetyl De... CAS#:13649-57-5 |
| Literature: Steroids, , vol. 13, p. 383 - 397 |
|
~%
21-Desacetyl De... CAS#:13649-57-5 |
| Literature: Steroids, , vol. 13, p. 383 - 397 |
![21-acetoxy-3β-hydroxy-2'-methyl-(5α,16β)-pregn-9(11)-eno[17,16-d]oxazol-20-one structure](https://image.chemsrc.com/caspic/047/19890-70-1.png)
![21-acetoxy-2'-methyl-(5α,16β)-pregn-9(11)-eno[17,16-d]oxazole-3,20-dione structure](https://image.chemsrc.com/caspic/009/19890-71-2.png)
![21-hydroxy-2'-methyl-16-β-5'H-pregna-1,4,9(11)-trieno[17,16-d]oxazole-3,20-dione 21-acetate structure](https://image.chemsrc.com/caspic/374/16119-56-5.png)
![3β-acetoxy-11β-hydroxy-2'-methyl-(5α,16β)-pregnano[17,16-d]oxazol-20-one structure](https://image.chemsrc.com/caspic/127/13649-87-1.png)
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| 21-desacetyl deflazacort |
| (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Glycoloyl-5-hydroxy-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one |
| 2H-Naphth[2',1':4,5]indeno[1,2-d]oxazol-2-one, 4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-5-hydroxy-6b-(2-hydroxyacetyl)-4a,6a,8-trimethyl-, (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)- |