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10184-70-0

10184-70-0 structure
10184-70-0 structure
  • Name: Anecortave
  • Chemical Name: (8S,10S,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
  • CAS Number: 10184-70-0
  • Molecular Formula: C21H28O4
  • Molecular Weight: 344.44
  • Catalog: Research Areas Cancer
  • Create Date: 2016-11-17 20:40:53
  • Modify Date: 2025-09-07 19:31:06
  • Anecortave (AL-4940) is an angiogenesis inhibitor. Anecortave is indicated for the study of exudative (wet) age-related macular degeneration as well as retinal tumors[1][2].
Name (8S,10S,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
Synonyms 21-Desacetyl Anecortave
17,21-Dihydroxy-pregna-4,9(11)-dien-3,20-dion
17,21-dihydroxy-pregna-4,9(11)-diene-3,20-dione
(8S,10S,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
Description Anecortave (AL-4940) is an angiogenesis inhibitor. Anecortave is indicated for the study of exudative (wet) age-related macular degeneration as well as retinal tumors[1][2].
Related Catalog
References

[1]. Kaiser PK, et al. Posterior juxtascleral depot administration of anecortave acetate. Surv Ophthalmol. 2007 Jan;52 Suppl 1:S62-9.  

[2]. Jockovich ME, et al. Anecortave acetate as single and adjuvant therapy in the treatment of retinal tumors of LH(BETA)T(AG) mice. Invest Ophthalmol Vis Sci. 2006 Apr;47(4):1264-8.  

Molecular Formula C21H28O4
Molecular Weight 344.44
Exact Mass 344.19900
PSA 74.60000
LogP 2.73090
119669-94-2 structure

119669-94-2

~%

10184-70-0 structure

10184-70-0

Literature: Breslow, Ronald; Brandl, Michael; Hunger, Juergen; Adams, Alan D. Journal of the American Chemical Society, 1987 , vol. 109, # 12 p. 3799 - 3801
108674-98-2 structure

108674-98-2

~%

10184-70-0 structure

10184-70-0

Literature: Breslow, Ronald; Brandl, Michael; Hunger, Juergen; Adams, Alan D. Journal of the American Chemical Society, 1987 , vol. 109, # 12 p. 3799 - 3801
7753-60-8 structure

7753-60-8

~%

10184-70-0 structure

10184-70-0

Literature: Audouin, Max; Levisalles, Jacques Bulletin de la Societe Chimique de France, 1985 , # 6 p. 1280 - 1284
428516-04-5 structure

428516-04-5

~%

10184-70-0 structure

10184-70-0

Literature: Bernstein et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 4830
566-35-8 structure

566-35-8

~%

10184-70-0 structure

10184-70-0

Literature: Fried; Sabo Journal of the American Chemical Society, 1957 , vol. 79, p. 1130,1137
113862-93-4 structure

113862-93-4

~%

10184-70-0 structure

10184-70-0

Literature: Fried; Sabo Journal of the American Chemical Society, 1957 , vol. 79, p. 1130,1137
74220-42-1 structure

74220-42-1

~%

10184-70-0 structure

10184-70-0

Literature: Bernstein et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 4830
76338-54-0 structure

76338-54-0

~%

10184-70-0 structure

10184-70-0

Literature: Bernstein et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 4830
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