H-PRO-PHE-OH

Modify Date: 2024-01-03 14:10:25

H-PRO-PHE-OH Structure
H-PRO-PHE-OH structure
 Common Name H-PRO-PHE-OH
CAS Number 13589-02-1 Molecular Weight 262.30
Density 1.2±0.1 g/cm3 Boiling Point 531.9±50.0 °C at 760 mmHg
Molecular Formula C14H18N2O3 Melting Point N/A
MSDS N/A Flash Point 275.5±30.1 °C

 Use of H-PRO-PHE-OH


H-Pro-Phe-OH is a dipeptide containing proline and phenylalanine, which can serve as a substrate for prolinase. H-Pro-Phe-OH can also be used for polypeptide synthesis, where phenylalanine is an aromatic amino acid that can inhibit the activity of Angiotensin-converting enzyme (ACE, HY-P2983)[1][2].

 Names

Name h-pro-phe-oh
Synonym More Synonyms

 H-PRO-PHE-OH Biological Activity

Description H-Pro-Phe-OH is a dipeptide containing proline and phenylalanine, which can serve as a substrate for prolinase. H-Pro-Phe-OH can also be used for polypeptide synthesis, where phenylalanine is an aromatic amino acid that can inhibit the activity of Angiotensin-converting enzyme (ACE, HY-P2983)[1][2].
Related Catalog
References

[1]. Majumder K, et al. Angiotensin I converting enzyme inhibitory peptides from simulated in vitro gastrointestinal digestion of cooked eggs. J Agric Food Chem. 2009 Jan 28;57(2):471-7.  

[2]. Priestman DA, et al. Prolinase and non-specific dipeptidase of human kidney. Biochem J. 1985 Nov 1;231(3):689-94.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 531.9±50.0 °C at 760 mmHg
Molecular Formula C14H18N2O3
Molecular Weight 262.30
Flash Point 275.5±30.1 °C
Exact Mass 262.131744
PSA 78.43000
LogP 0.67
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.568

 Synthetic Route

Z-Pro-Phe-OH structure

Z-Pro-Phe-OH

CAS#:17350-17-3

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H-PRO-PHE-OH Structure

H-PRO-PHE-OH

CAS#:13589-02-1
Literature: Freund, Matthias H.; Tsogoeva, Svetlana B. Synlett, 2011 , # 4 p. 503 - 507
N-Boc-L-Pro-L-Phe methyl ester structure

N-Boc-L-Pro-L-P...

CAS#:57177-79-4

~%

H-PRO-PHE-OH Structure

H-PRO-PHE-OH

CAS#:13589-02-1
Literature: Gautschi, Markus; Schmid, Joachim P.; Peppard, Terry L.; Ryan, Thomas P.; Tuorto, Raymond M.; Yang, Xiaogen Journal of Agricultural and Food Chemistry, 1997 , vol. 45, # 8 p. 3183 - 3189
Methyl L-phenylalaninate hydrochloride structure

Methyl L-phenyl...

CAS#:7524-50-7

~%

H-PRO-PHE-OH Structure

H-PRO-PHE-OH

CAS#:13589-02-1
Literature: Freund, Matthias H.; Tsogoeva, Svetlana B. Synlett, 2011 , # 4 p. 503 - 507
Boc-L-Proline structure

Boc-L-Proline

CAS#:15761-39-4

~%

H-PRO-PHE-OH Structure

H-PRO-PHE-OH

CAS#:13589-02-1
Literature: Gautschi, Markus; Schmid, Joachim P.; Peppard, Terry L.; Ryan, Thomas P.; Tuorto, Raymond M.; Yang, Xiaogen Journal of Agricultural and Food Chemistry, 1997 , vol. 45, # 8 p. 3183 - 3189
(S)-methyl 2-((S)-1-formylpyrrolidine-2-carbonylamino)-3-phenylpropanoate structure

(S)-methyl 2-((...

CAS#:129398-84-1

~%

H-PRO-PHE-OH Structure

H-PRO-PHE-OH

CAS#:13589-02-1
Literature: Sawayama; Itokawa; Shimada; Doi; Kimura; Nishim ura Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 2 p. 529 - 531
L-Proline, 1-formyl- structure

L-Proline, 1-formyl-

CAS#:13200-83-4

~%

H-PRO-PHE-OH Structure

H-PRO-PHE-OH

CAS#:13589-02-1
Literature: Sawayama; Itokawa; Shimada; Doi; Kimura; Nishim ura Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 2 p. 529 - 531
Proline structure

Proline

CAS#:147-85-3

~%

H-PRO-PHE-OH Structure

H-PRO-PHE-OH

CAS#:13589-02-1
Literature: Sawayama; Itokawa; Shimada; Doi; Kimura; Nishim ura Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 2 p. 529 - 531
Cbz-L-Pro-L-Phe-OMe structure

Cbz-L-Pro-L-Phe-OMe

CAS#:23631-72-3

~%

H-PRO-PHE-OH Structure

H-PRO-PHE-OH

CAS#:13589-02-1
Literature: Freund, Matthias H.; Tsogoeva, Svetlana B. Synlett, 2011 , # 4 p. 503 - 507
Z-Pro-OH structure

Z-Pro-OH

CAS#:1148-11-4

~%

H-PRO-PHE-OH Structure

H-PRO-PHE-OH

CAS#:13589-02-1
Literature: Freund, Matthias H.; Tsogoeva, Svetlana B. Synlett, 2011 , # 4 p. 503 - 507

 Synonyms

H-L-Pro-L-Phe-OH
N-L-Prolyl-L-phenylalanine
PRO-PHE
L-Pro-L-Phe-OH
pro-phecrystalline
Pro-Phe-OH
l-pro-l-phe
L-Prolyl-L-phenylalanine
L-Phenylalanine, L-prolyl-
PROLINE-PHENYLALANINE
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