BRD5529
Modify Date: 2025-08-25 19:42:19
BRD5529 structure
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Common Name | BRD5529 | ||
|---|---|---|---|---|
| CAS Number | 1358488-78-4 | Molecular Weight | 465.54 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H31N5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BRD5529BRD5529 is a selective CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction inhibitor with an IC50 of 8.6 μM. BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation and activation of CARD9, and demonstrates cellular activity and selectivity in CARD9-dependent pathways[1]. |
| Name | BRD5529 |
|---|
| Description | BRD5529 is a selective CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction inhibitor with an IC50 of 8.6 μM. BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation and activation of CARD9, and demonstrates cellular activity and selectivity in CARD9-dependent pathways[1]. |
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| Related Catalog | |
| Target |
IC50: 8.6 μM (CARD9-E3 ubiquitin ligase TRIM62)[1] |
| References |
| Molecular Formula | C25H31N5O4 |
|---|---|
| Molecular Weight | 465.54 |