SPP 86
Modify Date: 2025-08-26 14:03:59
SPP 86 structure
|
Common Name | SPP 86 | ||
|---|---|---|---|---|
| CAS Number | 1357349-91-7 | Molecular Weight | 277.32 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H15N5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of SPP 86SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. SPP-86 selectively inhibits RET- induced ERK1/2 phosphorylation in thyroid cancer cell lines[1]. |
| Name | SPP-86 |
|---|
| Description | SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. SPP-86 selectively inhibits RET- induced ERK1/2 phosphorylation in thyroid cancer cell lines[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 8 nM (RET)[1]. |
| References |
| Molecular Formula | C16H15N5 |
|---|---|
| Molecular Weight | 277.32 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| RIDADR | NONH for all modes of transport |