Palonosetron

Modify Date: 2025-08-25 16:28:44

Palonosetron structure	Common Name	Palonosetron
	CAS Number	135729-56-5	Molecular Weight	294.39
	Density	1.2±0.1 g/cm3	Boiling Point	470.4±45.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₂₂N₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	209.5±21.1 °C

Use of Palonosetron

Dehydro Palonosetron (RS 42358-197) is a potent, seslective and orally active 5-HT3 receptor antagonist. Dehydro Palonosetron has no effect on the activities of 5-HT1 receptors, 5-HT2 receptors or 5-HT4 receptors[1].

Name	Palonosetron
Synonym	More Synonyms

Description	Dehydro Palonosetron (RS 42358-197) is a potent, seslective and orally active 5-HT3 receptor antagonist. Dehydro Palonosetron has no effect on the activities of 5-HT1 receptors, 5-HT2 receptors or 5-HT4 receptors[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT3 Receptor
References	[1]. R M Eglen, et al. RS 42358-197, a novel and potent 5-HT3 receptor antagonist, in vitro and in vivo. J Pharmacol Exp Ther. 1993 Aug;266(2):535-43. [2]. B Costall, et al. The effect of the 5-HT3 receptor antagonist, RS-42358-197, in animal models of anxiety. Eur J Pharmacol. 1993 Mar 30;234(1):91-9.

Density	1.2±0.1 g/cm3
Boiling Point	470.4±45.0 °C at 760 mmHg
Molecular Formula	C₁₉H₂₂N₂O
Molecular Weight	294.39
Flash Point	209.5±21.1 °C
Exact Mass	296.188873
PSA	23.55000
LogP	2.61
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.646
InChIKey	DIDFYSQVOPVZQB-QGZVFWFLSA-N
SMILES	O=c1c2cccc3c2c(cn1C1CN2CCC1CC2)CCC3

Precursor 6
CAS#:135729-78-1 (S)-N-(1-AZABIC... CAS#:4242-18-6 5,6,7,8-Tetrahy... CAS#:110808-69-0 5,6,7,8-TETRAHY... CAS#:14935-18-3 5,6-Dihydro-1H,...
CAS#:120570-05-0 3-Aminoquinuclidine CAS#:296281-85-1 N,N-Diethyl-8-f...
DownStream 0

1H-Benz[de]isoquinolin-1-one, 2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-

2-(1-Azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one

Palonosteron

2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one

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Product Name: Palmitic acid
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Dayang Chem (Hangzhou) Co., Ltd.
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Product Name: Palonosetron
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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