clathrodin

Modify Date: 2025-08-31 14:24:50

clathrodin Structure
clathrodin structure
Common Name clathrodin
CAS Number 135383-64-1 Molecular Weight 231.25400
Density 1.382g/cm3 Boiling Point N/A
Molecular Formula C11H13N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of clathrodin


Clathrodin is a marine alkaloid that can be isolated from sponges of the genus, Agelas. Clathrodin is a modulator of voltage-gated sodium (NaV) channels. Clathrodin is a sodium channel neurotoxin influencing sodium channel ionic conductance[1][2].

 Names

Name N-[(E)-3-(2-amino-1H-imidazol-5-yl)prop-2-enyl]-1H-pyrrole-2-carboxamide
Synonym More Synonyms

 clathrodin Biological Activity

Description Clathrodin is a marine alkaloid that can be isolated from sponges of the genus, Agelas. Clathrodin is a modulator of voltage-gated sodium (NaV) channels. Clathrodin is a sodium channel neurotoxin influencing sodium channel ionic conductance[1][2].
Related Catalog
References

[1]. Rentas AL, et al. Effect of alkaloid toxins from tropical marine sponges on membrane sodium currents. Toxicon. 1995 Apr;33(4):491-7.  

 Chemical & Physical Properties

Density 1.382g/cm3
Molecular Formula C11H13N5O
Molecular Weight 231.25400
Exact Mass 231.11200
PSA 100.32000
LogP 1.08420
Index of Refraction 1.726
InChIKey PJKFCZYTTBYEHL-HNQUOIGGSA-N
SMILES Nc1ncc(C=CCNC(=O)c2ccc[nH]2)[nH]1

 Synonyms

Clathrodine
Clathrodin
N-(3-(2-Imino-2,3-dihydro-1H-imidazol-4-yl)-2-propenyl)-1H-pyrrole-2-carboxamide
1H-Pyrrole-2-carboxamide,N-(3-(2-amino-1H-imidazol-4-yl)-2-propenyl)-,(E)
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