Propargyl-PEG4-thiol

Modify Date: 2025-08-25 18:01:52

Propargyl-PEG4-thiol Structure
Propargyl-PEG4-thiol structure
Common Name Propargyl-PEG4-thiol
CAS Number 1347750-80-4 Molecular Weight 248.339
Density 1.1±0.1 g/cm3 Boiling Point 332.9±37.0 °C at 760 mmHg
Molecular Formula C11H20O4S Melting Point N/A
MSDS N/A Flash Point 155.1±26.5 °C

 Use of Propargyl-PEG4-thiol


Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Propargyl-PEG4-thiol
Synonym More Synonyms

 Propargyl-PEG4-thiol Biological Activity

Description Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Goswami LN, et al. Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 332.9±37.0 °C at 760 mmHg
Molecular Formula C11H20O4S
Molecular Weight 248.339
Flash Point 155.1±26.5 °C
Exact Mass 248.108231
LogP 0.09
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.475
InChIKey QFVYBCQBSOIWFU-UHFFFAOYSA-N
SMILES C#CCOCCOCCOCCOCCS

 Safety Information

Hazard Codes Xi

 Synonyms

3,6,9,12-Tetraoxapentadec-14-yne-1-thiol
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