Loracarbef-d5

Modify Date: 2024-01-10 15:13:06

Loracarbef-d5 Structure
Loracarbef-d5 structure
Common Name Loracarbef-d5
CAS Number 1346597-29-2 Molecular Weight 354.80
Density N/A Boiling Point N/A
Molecular Formula C16H11D5ClN3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Loracarbef-d5


Loracarbef-d5 is the deuterium labeled Loracarbef. Loracarbef, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class[1][2].

 Names

Name Loracarbef-d5

 Loracarbef-d5 Biological Activity

Description Loracarbef-d5 is the deuterium labeled Loracarbef. Loracarbef, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. M Hu, et al. Mechanisms of Transport of Quinapril in Caco-2 Cell Monolayers: Comparison With Cephalexin. Pharm Res. 1995 Aug;12(8):1120-5.

[3]. J W Dyke, et al. Antimicrobial Activity of New Antibiotics Against Bacterial Isolates From a Community Hospital. Chemotherapy. Sep-Oct 1993;39(5):315-21.

 Chemical & Physical Properties

Molecular Formula C16H11D5ClN3O4
Molecular Weight 354.80