Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (6R,7S)-7-<sub>[(2R)-2-Ammonio-2-phenylacetyl]amino</sub>-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, monohydrate
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: LORACARBEF (200 MG)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

121961-22-6

121961-22-6 structure

121961-22-6 structure

Name: Loracarbef hydrate
Chemical Name: loracarbef (200 mg)
CAS Number: 121961-22-6
Molecular Formula: C₁₆H₁₆ClN₃O_4.H₂O
Molecular Weight: 367.78400
Catalog: API Antibiotics Cephalosporin
Create Date: 2018-10-15 17:08:21
Modify Date: 2025-08-15 12:49:27
Loracarbef hydrate, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class[1][2].

Name	loracarbef (200 mg)
Synonyms	1-Azabicyclo4.2.0oct-2-ene-2-carboxylic acid,7-(2R)-aminophenylacetylamino-3-chloro-8-oxo-,monohydrate,(6R,7S) kt3777 Carbacefaclor 7-((aminophenylacetyl)amino)-3-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicaci

Description	Loracarbef hydrate, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Loracarbef hydrate demonstrates excellent activity against isolates of Escherichia coli and Klebsiella, Proteus and Salmonella species[2].
References	[1]. M Hu, et al. Mechanisms of Transport of Quinapril in Caco-2 Cell Monolayers: Comparison With Cephalexin. Pharm Res. 1995 Aug;12(8):1120-5. [2]. J W Dyke, et al. Antimicrobial Activity of New Antibiotics Against Bacterial Isolates From a Community Hospital. Chemotherapy. Sep-Oct 1993;39(5):315-21.

Boiling Point	662.2ºC at 760 mmHg
Melting Point	205-215° (dec) (Matsukuma)
Molecular Formula	C₁₆H₁₆ClN₃O_4.H₂O
Molecular Weight	367.78400
Flash Point	354.3ºC
Exact Mass	367.09300
PSA	121.96000
LogP	1.67560
Vapour Pressure	1.95E-18mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CL6175600

CHEMICAL NAME :: 1-Azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((aminophenylacetyl)amino)-3-chloro-8-oxo-, monohydrate, (6R-(6-alpha,7-beta(R*)))-

CAS REGISTRY NUMBER :: 121961-22-6

LAST UPDATED :: 199506

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C16-H16-Cl-N3-O4.H2-O

MOLECULAR WEIGHT :: 367.82

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 43,60,1993

RIDADR	NONH for all modes of transport

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