2′-Deoxy-2′-fluoro-N-methyladenosine

Modify Date: 2025-08-26 08:11:35

2′-Deoxy-2′-fluoro-N-methyladenosine Structure
2′-Deoxy-2′-fluoro-N-methyladenosine structure
Common Name 2′-Deoxy-2′-fluoro-N-methyladenosine
CAS Number 134444-58-9 Molecular Weight 283.26
Density N/A Boiling Point N/A
Molecular Formula C11H14FN5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2′-Deoxy-2′-fluoro-N-methyladenosine


2′-Deoxy-2′-fluoro-N-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2′-Deoxy-2′-fluoro-N-methyladenosine

 2′-Deoxy-2′-fluoro-N-methyladenosine Biological Activity

Description 2′-Deoxy-2′-fluoro-N-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C11H14FN5O3
Molecular Weight 283.26
InChIKey XVGMWRQRNLVRLF-HUKYDQBMSA-N
SMILES CNc1ncnc2c1ncn2C1OC(CO)C(O)C1F
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