2′-Deoxy-2′-fluoro-N-methyladenosine

Names

[ CAS No. ]:
134444-58-9

[ Name ]:
2′-Deoxy-2′-fluoro-N-methyladenosine

Biological Activity

[Description]:

2′-Deoxy-2′-fluoro-N-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C11H14FN5O3

[ Molecular Weight ]:
283.26

Related Compounds

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