Quilseconazole

Modify Date: 2025-08-20 15:41:27

Quilseconazole Structure
Quilseconazole structure
 Common Name Quilseconazole
CAS Number 1340593-70-5 Molecular Weight 513.37
Density N/A Boiling Point N/A
Molecular Formula C22H14F7N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Quilseconazole


Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes[1].

 Names

Name Quilseconazole

 Quilseconazole Biological Activity

Description Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes[1].
Related Catalog
Target

Fungal, Cyp51[1]

References

[1]. Lockhart SR, et al. The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2528-31.

 Chemical & Physical Properties

Molecular Formula C22H14F7N5O2
Molecular Weight 513.37
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