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1340593-70-5

1340593-70-5 structure
1340593-70-5 structure
  • Name: Quilseconazole
  • Chemical Name: Quilseconazole
  • CAS Number: 1340593-70-5
  • Molecular Formula: C22H14F7N5O2
  • Molecular Weight: 513.37
  • Catalog: Signaling Pathways Anti-infection Fungal
  • Create Date: 2019-06-30 13:48:16
  • Modify Date: 2024-01-02 06:34:40
  • Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes[1].

Name Quilseconazole
Description Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes[1].
Related Catalog
Target

Fungal, Cyp51[1]

References

[1]. Lockhart SR, et al. The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2528-31.

Molecular Formula C22H14F7N5O2
Molecular Weight 513.37