(S)-4CPG

Modify Date: 2025-08-26 22:42:08

(S)-4CPG Structure
(S)-4CPG structure
Common Name (S)-4CPG
CAS Number 134052-73-6 Molecular Weight 195.17
Density N/A Boiling Point N/A
Molecular Formula C9H9NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S)-4CPG


(S)-4CPG ((S)-4-Carboxyphenylglycine) is a potent mGluR2 agonist. (S)-4CPG reduces hyperalgesia and allodynia associated with sciatic nerve contraction injury in rats. (S)-4CPG can be used in research on neurological diseases[1][2].

 Names

Name (s)-4-carboxyphenylglycine

 (S)-4CPG Biological Activity

Description (S)-4CPG ((S)-4-Carboxyphenylglycine) is a potent mGluR2 agonist. (S)-4CPG reduces hyperalgesia and allodynia associated with sciatic nerve contraction injury in rats. (S)-4CPG can be used in research on neurological diseases[1][2].
Related Catalog
References

[1]. Hayashi Y, et al. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J Neurosci. 1994 May;14(5 Pt 2):3370-7.  

[2]. Fisher K, et al. Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats. Pain. 1998 Jul;77(1):59-66.  

 Chemical & Physical Properties

Molecular Formula C9H9NO4
Molecular Weight 195.17
Exact Mass 195.05300
PSA 100.62000
LogP 1.16950
InChIKey VTMJKPGFERYGJF-ZETCQYMHSA-N
SMILES NC(C(=O)O)c1ccc(C(=O)O)cc1
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