(E/Z)-AG490

Modify Date: 2024-01-11 12:43:25

(E/Z)-AG490 Structure
(E/Z)-AG490 structure
Common Name (E/Z)-AG490
CAS Number 134036-52-5 Molecular Weight 294.30500
Density 1.337g/cm3 Boiling Point 615.2ºC at 760mmHg
Molecular Formula C17H14N2O3 Melting Point 215ºC
MSDS N/A Flash Point 325.9ºC

 Use of (E/Z)-AG490


(E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 (HY-12000) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3.

 Names

Name ag 490
Synonym More Synonyms

 (E/Z)-AG490 Biological Activity

Description (E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 (HY-12000) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3.
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 Chemical & Physical Properties

Density 1.337g/cm3
Boiling Point 615.2ºC at 760mmHg
Melting Point 215ºC
Molecular Formula C17H14N2O3
Molecular Weight 294.30500
Flash Point 325.9ºC
Exact Mass 294.10000
PSA 93.35000
LogP 2.71208
Storage condition −20°C
Water Solubility ethanol: 5 mg/mL

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36
WGK Germany 1

 Synonyms

MFCD00209833