8-Hydroxyquinoline hemisulfate

Modify Date: 2024-01-02 14:37:03

8-Hydroxyquinoline hemisulfate structure	Common Name	8-Hydroxyquinoline hemisulfate
	CAS Number	134-31-6	Molecular Weight	388.394
	Density	1.26g/cm3	Boiling Point	267ºC at 760 mmHg
	Molecular Formula	C₉H₇NO_.1/₂H₂O₄S	Melting Point	~175 °C
	MSDS	Chinese USA	Flash Point	143.1ºC
	Symbol	GHS07	Signal Word	Warning

Use of 8-Hydroxyquinoline hemisulfate

8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.

Name	8-hydroxyquinoline sulfate
Synonym	More Synonyms

Description	8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial

Density	1.26g/cm3
Boiling Point	267ºC at 760 mmHg
Melting Point	~175 °C
Molecular Formula	C₉H₇NO_.1/₂H₂O₄S
Molecular Weight	388.394
Flash Point	143.1ºC
Exact Mass	388.072906
PSA	149.22000
LogP	4.30880
Vapour Pressure	8.34E-14mmHg at 25°C
Water Solubility	>=10 g/100 mL at 19 ºC

8-Hydroxyquinoline hemisulfate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VC8260000

CAS REGISTRY NUMBER :: 134-31-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 17

MOLECULAR FORMULA :: C18-H14-N2-O2.H2-O4-S

MOLECULAR WEIGHT :: 388.42

WISWESSER LINE NOTATION :: T66 BNJ JQ 2 &WSQQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 10 umol/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 2,191,1980 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81450 No. of Facilities: 669 (estimated) No. of Industries: 3 No. of Occupations: 8 No. of Employees: 8298 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81450 No. of Facilities: 256 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 4503 (estimated) No. of Female Employees: 3235 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R22
Safety Phrases	S36
RIDADR	2811
WGK Germany	1
RTECS	VC8260000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2933499090

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Selective growth-inhibitory effect of 8-hydroxyquinoline towards Clostridium difficile and Bifidobacterium longum subsp. longum in co-culture analysed by flow cytometry.

J. Med. Microbiol. 63(Pt 12) , 1663-9, (2014)

The major risk factor for Clostridium difficile infection (CDI) is the use of antibiotics owing to the disruption of the equilibrium of the host gut microbiota. To preserve the beneficial resident pro...

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

J. Sci. Ind. Res. 65(10) , 808, (2006)

Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI typ...

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chem. Res. Toxicol. 23 , 1215-22, (2010)

Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...

8-Quinolinol, sulfate (2:1) (salt)

MFCD00013095

Bis(8-hydroxyquinolinium) sulphate

8-hydroxyquinoline sulphate

8-Quinolinone Sulfate Monohydrate

EINECS 205-137-1

Oxyquinoline Sulfate

8-Hydroxyquinoline hemisulfate salt

8-Quinolinol hemisulfate salt

Chinosol

bis(8-hydroxyquinolinium) sulfate

8-Quinolinol sulfate (2:1)

8-Hydroxyquinoline Sulfate Monohydrate

Quinolin-8-ol sulfate (2:1)

Quinolin-8-ol sulfate

Oxine Sulfate Monohydrate

bis(8-hydroxyquinolin-1-ium) sulfate

Chinosol Monohydrate

8-quinolinol sulfate (2:1) (salt)

Hydroxyquinoline sulfate

8-Quinolinol Sulfate Monohydrate

8-Hydroxyquinoline sulfate

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 8-Hydroxyquinoline hemisulfate
Price: ￥108.0/100g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: 8-Hydroxyquinoline sulfate
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 8-Hydroxyquinoline sulfate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 8-Hydroxyquinoline sulfate
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFU CHEM -- 8-Hydroxyquinoline sulfate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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