PERK-IN-6
Modify Date: 2024-04-06 22:22:24
PERK-IN-6 structure
|
Common Name | PERK-IN-6 | ||
|---|---|---|---|---|
| CAS Number | 1337532-14-5 | Molecular Weight | 398.46 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H22N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PERK-IN-6PERK-IN-6 (Compound 5) is a PERK inhibitor with an IC50 of 2.5 nM[1]. |
| Name | PERK-IN-6 |
|---|
| Description | PERK-IN-6 (Compound 5) is a PERK inhibitor with an IC50 of 2.5 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2.5 nM (PERK)[1] |
| In Vitro | 在 A549 细胞中，PERK-IN-6 (Compound 5) 抑制 thapsigargin 诱导的 PERK 自磷酸化，IC50 为 0.1-0.3 μΜ[1]。 |
| In Vivo | SD 大鼠静脉注射 PERK-IN-6 (Compound 5) 后血液清除率为 10.5 mL/min/kg [1]。 |
| References |
| Molecular Formula | C23H22N6O |
|---|---|
| Molecular Weight | 398.46 |