1337532-14-5
1337532-14-5 structure
- Name: PERK-IN-6
- Chemical Name: PERK-IN-6
- CAS Number: 1337532-14-5
- Molecular Formula: C23H22N6O
- Molecular Weight: 398.46
- Catalog: Signaling Pathways Cell Cycle/DNA Damage PERK
- Create Date: 2023-06-20 22:53:46
- Modify Date: 2024-04-06 22:22:24
-
PERK-IN-6 (Compound 5) is a PERK inhibitor with an IC50 of 2.5 nM[1].
| Name | PERK-IN-6 |
|---|
| Description | PERK-IN-6 (Compound 5) is a PERK inhibitor with an IC50 of 2.5 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2.5 nM (PERK)[1] |
| In Vitro | 在 A549 细胞中，PERK-IN-6 (Compound 5) 抑制 thapsigargin 诱导的 PERK 自磷酸化，IC50 为 0.1-0.3 μΜ[1]。 |
| In Vivo | SD 大鼠静脉注射 PERK-IN-6 (Compound 5) 后血液清除率为 10.5 mL/min/kg [1]。 |
| References |
| Molecular Formula | C23H22N6O |
|---|---|
| Molecular Weight | 398.46 |