Prostaglandin B2

Modify Date: 2024-01-02 14:59:38

Prostaglandin B2 Structure
Prostaglandin B2 structure
Common Name Prostaglandin B2
CAS Number 13367-85-6 Molecular Weight 334.45
Density 1.1±0.1 g/cm3 Boiling Point 537.0±50.0 °C at 760 mmHg
Molecular Formula C20H30O4 Melting Point N/A
MSDS Chinese USA Flash Point 292.6±26.6 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Use of Prostaglandin B2


Prostaglandin B2 is a prostaglandin. Prostaglandin B2 is the main substance in cord blood mesenchymal stem cells, to inhibit DC-T Cell proliferation. Prostaglandin B2 also induces cutaneous vasoconstriction of the canine hind paw[1][2].

 Names

Name prostaglandin B2
Synonym More Synonyms

 Prostaglandin B2 Biological Activity

Description Prostaglandin B2 is a prostaglandin. Prostaglandin B2 is the main substance in cord blood mesenchymal stem cells, to inhibit DC-T Cell proliferation. Prostaglandin B2 also induces cutaneous vasoconstriction of the canine hind paw[1][2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Greenberg S, Engelbrecht JA, Wilson WR. Prostaglandin B2-induced cutaneous vasoconstriction of the canine hind paw. Circ Res. 1974 Apr;34(4):491-7.  

[2]. van den Berk LC, et al. Cord blood mesenchymal stem cells suppress DC-T Cell proliferation via prostaglandin B2. Stem Cells Dev. 2014 Jul 15;23(14):1582-93.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 537.0±50.0 °C at 760 mmHg
Molecular Formula C20H30O4
Molecular Weight 334.45
Flash Point 292.6±26.6 °C
Exact Mass 334.214417
PSA 74.60000
LogP 3.24
Appearance of Characters solution
Vapour Pressure 0.0±3.2 mmHg at 25°C
Index of Refraction 1.564
Storage condition −20°C
Water Solubility ethanol: ~100 mg/mL

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H319-H336
Supplemental HS Repeated exposure may cause skin dryness or cracking.
Precautionary Statements P210-P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313-P403 + P235
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn,Xi,F
Risk Phrases 20/21/22-67-66-36-11
Safety Phrases 36/37-26
RIDADR UN 1231 3/PG 2
WGK Germany 3

 Articles31

More Articles
Identification of prostamides, fatty acyl ethanolamines, and their biosynthetic precursors in rabbit cornea.

J. Lipid Res. 56 , 1419-33, (2015)

Arachidonoyl ethanolamine (anandamide) and pros-taglandin ethanolamines (prostamides) are biologically active derivatives of arachidonic acid. Although available through different precursor phospholip...

Differences in the Neuroprotective Effect of Orally Administered Virgin Olive Oil (Olea europaea) Polyphenols Tyrosol and Hydroxytyrosol in Rats.

J. Agric. Food Chem. 63 , 5957-63, (2015)

The neuroprotective effect of virgin olive oil (VOO) polyphenols has been related to their antioxidant effect. The main objective was to analyze how tyrosol and hydroxytyrosol contribute to the antiox...

Cord blood mesenchymal stem cells suppress DC-T Cell proliferation via prostaglandin B2.

Stem Cells Dev. 23(14) , 1582-93, (2014)

Immune suppression is a very stable property of multipotent stromal cells also known as mesenchymal stem cells (MSCs). All cell lines tested showed robust immune suppression not affected by a long cul...

 Synonyms

(5Z,13E,15R)-15-Hydroxy-9-oxoprosta-5,8(12),13-trien-1-oic acid
MFCD00065730
EINECS 234-237-8
Prostaglandin B2
(5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,8(12),13-trien-1-oic acid PGB2
Prosta-5,8(12),13-trien-1-oic acid, 15-hydroxy-9-oxo-, (5Z,13E,15R)-