N-Desmethyl Apalutamide
Modify Date: 2025-08-21 18:52:35
N-Desmethyl Apalutamide structure
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Common Name | N-Desmethyl Apalutamide | ||
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| CAS Number | 1332391-11-3 | Molecular Weight | 463.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H13F4N5O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of N-Desmethyl ApalutamideN-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration[1][2][3]. |
| Name | N-Desmethyl Apalutamide |
|---|
| Description | N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration[1][2][3]. |
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| Related Catalog | |
| Target |
CYP3A4 and CYP2B6[1];Androgen receptor[2] |
| References |
| Molecular Formula | C20H13F4N5O2S |
|---|---|
| Molecular Weight | 463.41 |
| Storage condition | 2-8°C |