DC Chemicals Limited
China
Product Name: N-Desmethyl Pimavanserin
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Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

639863-77-7

639863-77-7 structure

639863-77-7 structure

Name: N-Desmethyl Pimavanserin
Chemical Name: N-Desmethyl Pimavanserin
CAS Number: 639863-77-7
Molecular Formula: C₂₄H₃₂FN₃O₂
Molecular Weight: 413.53
Create Date: 2020-01-23 13:15:51
Modify Date: 2024-01-09 20:29:55
N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.

Name	N-Desmethyl Pimavanserin

Description	N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.
In Vitro	The mean plasma half-lives for Pimavanserin and its metabolite N-Desmethyl Pimavanserin (AC-279) are 57 hours and 200 hours, respectively.
References	[1]. Vanover KE, et al. Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist. J Pharmacol Exp Ther. 2006 May;317(2):910-8.

Molecular Formula	C₂₄H₃₂FN₃O₂
Molecular Weight	413.53