5alpha-Hydroxycostic acid

Modify Date: 2025-08-24 23:20:04

5alpha-Hydroxycostic acid structure	Common Name	5alpha-Hydroxycostic acid
	CAS Number	132185-83-2	Molecular Weight	250.333
	Density	1.1±0.1 g/cm3	Boiling Point	406.4±38.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	213.8±23.3 °C

Use of 5alpha-Hydroxycostic acid

5α-Hydroxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-Hydroxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways[1].

Name	2-[(2R,4aR,8aR)-8a-Hydroxy-4a-methyl-8-methylenedecahydro-2-naphthalenyl]acrylic acid
Synonym	More Synonyms

Description	5α-Hydroxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-Hydroxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
References	[1]. Liang N, et, al. Two natural eudesmane-type sesquiterpenes from Laggera alata inhibit angiogenesis and suppress breast cancer cell migration through VEGF- and Angiopoietin 2-mediated signaling pathways. Int J Oncol. 2017 Jul;51(1):213-222.

Density	1.1±0.1 g/cm3
Boiling Point	406.4±38.0 °C at 760 mmHg
Molecular Formula	C₁₅H₂₂O₃
Molecular Weight	250.333
Flash Point	213.8±23.3 °C
Exact Mass	250.156891
PSA	57.53000
LogP	3.19
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.540

Hazard Codes	Xi

2-[(2R,4aR,8aR)-8a-Hydroxy-4a-methyl-8-methylenedecahydro-2-naphthalenyl]acrylic acid

2-Naphthaleneacetic acid, decahydro-8a-hydroxy-4a-methyl-α,8-bis(methylene)-, (2R,4aR,8aR)-

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 5α-Hydroxycosticacid
Price: Check
Purity: 96.5%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: 5α-Hydroxycostic acid
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5ALFA-HYDROXYCOSTIC ACID
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.