Top Suppliers:I want be here



132185-83-2

132185-83-2 structure
132185-83-2 structure
  • Name: 5alpha-Hydroxycostic acid
  • Chemical Name: 2-[(2R,4aR,8aR)-8a-Hydroxy-4a-methyl-8-methylenedecahydro-2-naphthalenyl]acrylic acid
  • CAS Number: 132185-83-2
  • Molecular Formula: C15H22O3
  • Molecular Weight: 250.333
  • Catalog: Natural product Sesquiter
  • Create Date: 2017-05-07 07:24:35
  • Modify Date: 2025-08-24 23:20:04
  • 5α-Hydroxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-Hydroxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways[1].

Name 2-[(2R,4aR,8aR)-8a-Hydroxy-4a-methyl-8-methylenedecahydro-2-naphthalenyl]acrylic acid
Synonyms 2-[(2R,4aR,8aR)-8a-Hydroxy-4a-methyl-8-methylenedecahydro-2-naphthalenyl]acrylic acid
2-Naphthaleneacetic acid, decahydro-8a-hydroxy-4a-methyl-α,8-bis(methylene)-, (2R,4aR,8aR)-
Description 5α-Hydroxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-Hydroxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways[1].
Related Catalog
References

[1]. Liang N, et, al. Two natural eudesmane-type sesquiterpenes from Laggera alata inhibit angiogenesis and suppress breast cancer cell migration through VEGF- and Angiopoietin 2-mediated signaling pathways. Int J Oncol. 2017 Jul;51(1):213-222.

Density 1.1±0.1 g/cm3
Boiling Point 406.4±38.0 °C at 760 mmHg
Molecular Formula C15H22O3
Molecular Weight 250.333
Flash Point 213.8±23.3 °C
Exact Mass 250.156891
PSA 57.53000
LogP 3.19
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.540
Hazard Codes Xi
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.