DOTAP chloride
Modify Date: 2025-08-25 19:34:35
DOTAP chloride structure
|
Common Name | DOTAP chloride | ||
|---|---|---|---|---|
| CAS Number | 132172-61-3 | Molecular Weight | 663.08900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C42H80ClNO4 | Melting Point | 35-38ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of DOTAP chlorideDOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1]. |
| Name | 2,3-di(octadec-9-enoyloxy)propyl-trimethylazanium |
|---|---|
| Synonym | More Synonyms |
| Description | DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: Cationic Lipid[1] |
| In Vitro | liposomes are reorganized by associating with DNA. The transfection efficiency of DOTAP liposomes is mainly influenced by lipid composition and cell type, but not by size or zeta potential[1]. |
| References |
| Melting Point | 35-38ºC |
|---|---|
| Molecular Formula | C42H80ClNO4 |
| Molecular Weight | 663.08900 |
| Exact Mass | 662.60900 |
| PSA | 52.60000 |
| LogP | 12.22260 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
A promising cancer gene therapy agent based on the matrix protein of vesicular stomatitis virus.
FASEB J. 22 , 4272-80, (2008) The matrix (M) protein of vesicular stomatitis virus (VSV) plays a key role in inducing cell apoptosis during infection. To investigate whether M protein-mediated apoptosis could be used in cancer the... |
| 2,3-dioleyloxypropyltrimethylammonium chloride |
| 1,2-dioleoyl-3-trimethylammonium-propane chloride |
| 1,2-dioleoyl-3-trimethylammonium-propane chloride salt |
| DOTAP chloride |