Peptide 74

Modify Date: 2024-01-13 07:01:40

Peptide 74 Structure
Peptide 74 structure
Common Name Peptide 74
CAS Number 132116-39-3 Molecular Weight 1558.79
Density N/A Boiling Point N/A
Molecular Formula C62H107N23O20S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Peptide 74


Peptide 74 is a synthetic peptide containing the prodomain sequence of matrix metalloproteinase (MMP). Peptide 74 inhibits the activated form of the 72-kDa type IV collagenase in vitro[1].

 Names

Name peptide 74

 Peptide 74 Biological Activity

Description Peptide 74 is a synthetic peptide containing the prodomain sequence of matrix metalloproteinase (MMP). Peptide 74 inhibits the activated form of the 72-kDa type IV collagenase in vitro[1].
Related Catalog
In Vitro Peptide 74 (30 μM) reduces both A2058 and HT 1080 tumor cell invasion by 60-80%[1]. Peptide 74 (30 μM) shows no cytotoxic action and does not inhibit chemotaxis or affect HT1080 and A2058 human tumor cells number[1].
References

[1]. A Melchiori, et al. Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment. Cancer Res. 1992 Apr 15;52(8):2353-6.

[2]. P P Lee, et al. Functional role of matrix metalloproteinases (MMPs) in mammary epithelial cell development. J Cell Physiol. 2001 Jul;188(1):75-88.

 Chemical & Physical Properties

Molecular Formula C62H107N23O20S2
Molecular Weight 1558.79