Taiwan Oyi peptide Co. Ltd
China
Product Name: PEPTIDE 74
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
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132116-39-3

132116-39-3 structure

132116-39-3 structure

Name: Peptide 74
Chemical Name: peptide 74
CAS Number: 132116-39-3
Molecular Formula: C₆₂H₁₀₇N₂₃O₂₀S₂
Molecular Weight: 1558.79
Catalog: Research Areas Cancer
Create Date: 2018-06-16 14:22:11
Modify Date: 2024-01-13 07:01:40
Peptide 74 is a synthetic peptide containing the prodomain sequence of matrix metalloproteinase (MMP). Peptide 74 inhibits the activated form of the 72-kDa type IV collagenase in vitro[1].

Name	peptide 74

Description	Peptide 74 is a synthetic peptide containing the prodomain sequence of matrix metalloproteinase (MMP). Peptide 74 inhibits the activated form of the 72-kDa type IV collagenase in vitro[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Peptide 74 (30 μM) reduces both A2058 and HT 1080 tumor cell invasion by 60-80%[1]. Peptide 74 (30 μM) shows no cytotoxic action and does not inhibit chemotaxis or affect HT1080 and A2058 human tumor cells number[1].
References	[1]. A Melchiori, et al. Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment. Cancer Res. 1992 Apr 15;52(8):2353-6. [2]. P P Lee, et al. Functional role of matrix metalloproteinases (MMPs) in mammary epithelial cell development. J Cell Physiol. 2001 Jul;188(1):75-88.

Molecular Formula	C₆₂H₁₀₇N₂₃O₂₀S₂
Molecular Weight	1558.79