PI3Kγ inhibitor 2

Modify Date: 2025-08-25 21:03:06

PI3Kγ inhibitor 2 Structure
PI3Kγ inhibitor 2 structure
Common Name PI3Kγ inhibitor 2
CAS Number 1315538-79-4 Molecular Weight 433.38
Density N/A Boiling Point N/A
Molecular Formula C20H18F3N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PI3Kγ inhibitor 2


PI3Kγ inhibitor 2 (Compound 16) is an orally bioavailable, CNS-penetrant, isoform selective PI3Kγ inhibitor with a Ki of 4 nM[1].

 Names

Name PI3Kγ inhibitor 2

 PI3Kγ inhibitor 2 Biological Activity

Description PI3Kγ inhibitor 2 (Compound 16) is an orally bioavailable, CNS-penetrant, isoform selective PI3Kγ inhibitor with a Ki of 4 nM[1].
Related Catalog
Target

PI3Kγ:4 nM (Ki)

References

[1]. Come JH, et al. Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS). J Med Chem. 2018 Jun 28;61(12):5245-5256.

 Chemical & Physical Properties

Molecular Formula C20H18F3N5O3
Molecular Weight 433.38
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