E3 ligase Ligand-Linker Conjugates 37

Modify Date: 2025-08-29 20:25:27

E3 ligase Ligand-Linker Conjugates 37 structure	Common Name	E3 ligase Ligand-Linker Conjugates 37
	CAS Number	1312302-14-9	Molecular Weight	660.80
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₇H₄₈N₄O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of E3 ligase Ligand-Linker Conjugates 37

E3 ligase Ligand-Linker Conjugates 37 incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 37 can be used to design PROTAC degrader[1].

Name	E3 ligase Ligand-Linker Conjugates 37

Description	E3 ligase Ligand-Linker Conjugates 37 incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 37 can be used to design PROTAC degrader[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	cIAP1
References	[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.

Molecular Formula	C₃₇H₄₈N₄O₇
Molecular Weight	660.80
InChIKey	IMJARMFRGASVMW-UHFFFAOYSA-N
SMILES	CC(C)CC(NC(=O)C(O)C(Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCCOCCOCCN

Hazard Codes	Xi

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