JHDM-IN-1

Modify Date: 2024-01-30 18:29:24

JHDM-IN-1 structure	Common Name	JHDM-IN-1
	CAS Number	1310809-17-6	Molecular Weight	491.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₂₉N₃O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JHDM-IN-1

JHDM-IN-1 (Compound 1) is a Jumonji C domain-containing HDMs (JHDM) inhibitor with IC50s of 3.4, 4.3, 5.9, 10 and 43 μM against JMJD2C, JMJD2A, JMJD2E, PHF8 and JMJD3, respectively[1].

Name	JHDM-IN-1

Description	JHDM-IN-1 (Compound 1) is a Jumonji C domain-containing HDMs (JHDM) inhibitor with IC50s of 3.4, 4.3, 5.9, 10 and 43 μM against JMJD2C, JMJD2A, JMJD2E, PHF8 and JMJD3, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Demethylase
Target	IC50: 3.4 μM (JMJD2C), 4.3 μM (JMJD2A), 5.9 μM (JMJD2E), 10 μM (PHF8), 22 μM (FIH), 31 μM (PHD3), 43 μM (JMJD3), 54 μM (PHD1), 83 μM (PHD2), 620 μM (LSD1)[1]
In Vitro	JHDM-IN-1 (Compound 1) 抑制 FIH、PHD3、PHD1、PHD2 和 LSD1 的 IC50 分别为 22、31、54、83 和 620 μM[1]。 JHDM-IN-1 (0-100 μM) 处理 48 h 后对 KYSE150 细胞生长无抑制作用[1]。
References	[1]. Luo X, et al. A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases. J Am Chem Soc. 2011 Jun 22;133(24):9451-6.

Molecular Formula	C₂₇H₂₉N₃O₆
Molecular Weight	491.54

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com