ICMT-IN-21

Modify Date: 2024-05-30 12:46:45

ICMT-IN-21 Structure
ICMT-IN-21 structure
 Common Name ICMT-IN-21
CAS Number 1310740-69-2 Molecular Weight 471.70
Density N/A Boiling Point N/A
Molecular Formula C22H33NO4S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ICMT-IN-21


ICMT-IN-21 (compound 6ag) is an ICMT inhibitor (IC50=8.8 μM), a sulfonamide-modified farnesyl cysteine (SMFC). The farnesyl and carboxylic acid motifs of ICMT-IN-21 are important structures for inhibiting ICMT[1].

 Names

Name ICMT-IN-21

 ICMT-IN-21 Biological Activity

Description ICMT-IN-21 (compound 6ag) is an ICMT inhibitor (IC50=8.8 μM), a sulfonamide-modified farnesyl cysteine (SMFC). The farnesyl and carboxylic acid motifs of ICMT-IN-21 are important structures for inhibiting ICMT[1].
Related Catalog
Target

IC50: 8.8 μM (ICMT)[1]

References

[1]. Majmudar JD, et al. Probing the isoprenylcysteine carboxyl methyltransferase (Icmt) binding pocket: sulfonamide modified farnesyl cysteine (SMFC) analogs as Icmt inhibitors. Bioorg Med Chem Lett. 2011 May 1;21(9):2616-20.  

 Chemical & Physical Properties

Molecular Formula C22H33NO4S3
Molecular Weight 471.70
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Chemsrc provides ICMT-IN-21(CAS#:1310740-69-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of ICMT-IN-21 are included as well.>> amp version: ICMT-IN-21

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