ICMT-IN-21

Names

[ CAS No. ]:
1310740-69-2

[ Name ]:
ICMT-IN-21

Biological Activity

[Description]:

ICMT-IN-21 (compound 6ag) is an ICMT inhibitor (IC50=8.8 μM), a sulfonamide-modified farnesyl cysteine (SMFC). The farnesyl and carboxylic acid motifs of ICMT-IN-21 are important structures for inhibiting ICMT[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

IC50: 8.8 μM (ICMT)[1]


[References]

[1]. Majmudar JD, et al. Probing the isoprenylcysteine carboxyl methyltransferase (Icmt) binding pocket: sulfonamide modified farnesyl cysteine (SMFC) analogs as Icmt inhibitors. Bioorg Med Chem Lett. 2011 May 1;21(9):2616-20.  

Chemical & Physical Properties

[ Molecular Formula ]:
C22H33NO4S3

[ Molecular Weight ]:
471.70

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.