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1310740-69-2

1310740-69-2 structure

1310740-69-2 structure

Name: ICMT-IN-21
Chemical Name: ICMT-IN-21
CAS Number: 1310740-69-2
Molecular Formula: C₂₂H₃₃NO₄S₃
Molecular Weight: 471.70
Catalog: Research Areas Cancer
Create Date: 2024-05-30 12:46:45
Modify Date: 2024-05-30 12:46:45
ICMT-IN-21 (compound 6ag) is an ICMT inhibitor (IC50=8.8 μM), a sulfonamide-modified farnesyl cysteine (SMFC). The farnesyl and carboxylic acid motifs of ICMT-IN-21 are important structures for inhibiting ICMT[1].

Name	ICMT-IN-21

Description	ICMT-IN-21 (compound 6ag) is an ICMT inhibitor (IC50=8.8 μM), a sulfonamide-modified farnesyl cysteine (SMFC). The farnesyl and carboxylic acid motifs of ICMT-IN-21 are important structures for inhibiting ICMT[1].
Related Catalog	Research Areas >> Cancer
Target	IC50: 8.8 μM (ICMT)[1]
References	[1]. Majmudar JD, et al. Probing the isoprenylcysteine carboxyl methyltransferase (Icmt) binding pocket: sulfonamide modified farnesyl cysteine (SMFC) analogs as Icmt inhibitors. Bioorg Med Chem Lett. 2011 May 1;21(9):2616-20.

Molecular Formula	C₂₂H₃₃NO₄S₃
Molecular Weight	471.70

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