bromfenvinphos-methyl

Modify Date: 2024-01-21 16:50:47

bromfenvinphos-methyl Structure
bromfenvinphos-methyl structure
Common Name bromfenvinphos-methyl
CAS Number 13104-21-7 Molecular Weight 375.96800
Density 1.63g/cm3 Boiling Point 382.2ºC at 760mmHg
Molecular Formula C10H10BrCl2O4P Melting Point N/A
MSDS USA Flash Point 185ºC
Symbol GHS06
GHS06
Signal Word Danger

 Names

Name [(E)-2-bromo-1-(2,4-dichlorophenyl)ethenyl] dimethyl phosphate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.63g/cm3
Boiling Point 382.2ºC at 760mmHg
Molecular Formula C10H10BrCl2O4P
Molecular Weight 375.96800
Flash Point 185ºC
Exact Mass 373.88800
PSA 54.57000
LogP 5.10420
Vapour Pressure 1.05E-05mmHg at 25°C
Index of Refraction 1.564
Storage condition APPROX 4°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TB8460000
CHEMICAL NAME :
Phosphoric acid, 2-bromo-1-(2,4-dichlorophenyl)vinyl dimethyl ester
CAS REGISTRY NUMBER :
13104-21-7
LAST UPDATED :
199709
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H10-Br-Cl2-O4-P
MOLECULAR WEIGHT :
375.98
WISWESSER LINE NOTATION :
GR CG DYU1EOPO&O1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
225 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCTKAG Bromatologia i Chemia Toksykologiczna. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.4- 1971- Volume(issue)/page/year: 9,283,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APYPAY Acta Physiologica Polonica. (Karger-Libri, POB CH-4009, Warszawa, Switzerland) V.1-41, 1950-90. Volume(issue)/page/year: 32,507,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
405 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APYPAY Acta Physiologica Polonica. (Karger-Libri, POB CH-4009, Warszawa, Switzerland) V.1-41, 1950-90. Volume(issue)/page/year: 31,575,1980 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
792 mg/kg/12W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
BCTKAG Bromatologia i Chemia Toksykologiczna. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.4- 1971- Volume(issue)/page/year: 19,61,1986
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1134 mg/kg/28D-I
TOXIC EFFECTS :
Liver - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
REFERENCE :
APYPAY Acta Physiologica Polonica. (Karger-Libri, POB CH-4009, Warszawa, Switzerland) V.1-41, 1950-90. Volume(issue)/page/year: 31,575,1980
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1536 mg/kg/17W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
REFERENCE :
APYPAY Acta Physiologica Polonica. (Karger-Libri, POB CH-4009, Warszawa, Switzerland) V.1-41, 1950-90. Volume(issue)/page/year: 32,507,1981

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases S36
RIDADR UN2811 6.1/PG 3
RTECS TB8460000
HS Code 2919900090

 Customs

HS Code 2919900090
Summary 2919900090 other phosphoric esters and their salts, including lactophosphates; their halogenated, sulphonated, nitrated or nitrosated derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

 Articles21

More Articles
Estimation of cis-diamminedichloroplatinum (II) binding to purine bases of calf thymus DNA using [14C]methylbromphenvinphos.

J. Biochem. Biophys. Methods 7(2) , 171-3, (1983)

The effect of methylbromophenvinfos (Polfos) on some enzymes in vivo and in vitro. I. In vivo studies.

Pol. J. Pharmacol. Pharm. 39(4) , 361-70, (1987)

The experiment was carried out on Wistar rats receiving orally either oil or oily solution of methylbromophenvinfos (Polfos) either in a single dose of 0.5 LD50, or doses of 0.1 LD50 once daily for a ...

Excretion and peripheral metabolism of 1, 2-3H-testosterone and androgens in rats following intoxication with organophosphorous insecticides. 1--Acute exposure.

J. Appl. Toxicol. 4(5) , 261-4, (1984)

The effects of methylbromphenvinfos (MBFV) and fenitrothion on androgen levels, excretion and peripheral metabolism were studied in male rats. The insecticides were administered orally in high, single...

 Synonyms

Polphos
Methylbromphenvinphos
Polfos
IPO 63
Shell SD-8988
METHYLBROMFENVINPHOS
Bromfenvinphos-methyl
ENT 27,043