SCO-L-Lysine

Modify Date: 2024-02-28 17:13:15

SCO-L-Lysine Structure
SCO-L-Lysine structure
Common Name SCO-L-Lysine
CAS Number 1309581-49-4 Molecular Weight 296.36200
Density N/A Boiling Point N/A
Molecular Formula C15H24N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SCO-L-Lysine


SCO-L-Lysine contains a SCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. SCO-L-Lysine can be incorporated into the protein of interest by the tRNAPyl/PylRSAF synthetase[1].

 Names

Name N-ε-((cyclooct-2-yn-1-yloxy)carbonyl)-L-lysine
Synonym More Synonyms

 SCO-L-Lysine Biological Activity

Description SCO-L-Lysine contains a SCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. SCO-L-Lysine can be incorporated into the protein of interest by the tRNAPyl/PylRSAF synthetase[1].
Related Catalog
References

[1]. Anandi Kugele, et al. In situ EPR spectroscopy of a bacterial membrane transporter using an expanded genetic code. Chem Commun (Camb). 2021 Dec 3;57(96):12980-12983.  

 Chemical & Physical Properties

Molecular Formula C15H24N2O4
Molecular Weight 296.36200
Exact Mass 296.17400
PSA 101.65000
LogP 2.72210

 Synonyms

l-lysine, n6-[(2-cyclooctyn-1-yloxy)carbonyl]-
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