1309581-49-4

1309581-49-4 structure

Name: SCO-L-Lysine
Chemical Name: N-ε-((cyclooct-2-yn-1-yloxy)carbonyl)-L-lysine
CAS Number: 1309581-49-4
Molecular Formula: C₁₅H₂₄N₂O₄
Molecular Weight: 296.36200
Catalog: Research Areas Others
Create Date: 2016-03-19 11:45:07
Modify Date: 2025-08-26 18:35:37
SCO-L-Lysine contains a SCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. SCO-L-Lysine can be incorporated into the protein of interest by the tRNAPyl/PylRSAF synthetase[1].

Name	N-ε-((cyclooct-2-yn-1-yloxy)carbonyl)-L-lysine
Synonyms	l-lysine, n6-[(2-cyclooctyn-1-yloxy)carbonyl]-

Description	SCO-L-Lysine contains a SCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. SCO-L-Lysine can be incorporated into the protein of interest by the tRNAPyl/PylRSAF synthetase[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Anandi Kugele, et al. In situ EPR spectroscopy of a bacterial membrane transporter using an expanded genetic code. Chem Commun (Camb). 2021 Dec 3;57(96):12980-12983.