KHK-IN-1 hydrochloride

Modify Date: 2025-08-21 07:56:35

KHK-IN-1 hydrochloride structure	Common Name	KHK-IN-1 hydrochloride
	CAS Number	1303470-48-5	Molecular Weight	459.011
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₇ClN₈S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of KHK-IN-1 hydrochloride

KHK-IN-1 Hcl is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK.

Name	KHK-IN-1 hydrochloride
Synonym	More Synonyms

Description	KHK-IN-1 Hcl is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others
References	[1]. Maryanoff BE, et al. Pyrimidinopyrimidine inhibitors of ketohexokinase: exploring the ring C2 group that interacts with Asp-27B in the ligand binding pocket. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5326-9. [2]. Maryanoff BE, et al. Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site. ACS Med Chem Lett. 2011 Apr 18;2(7):538-43.

Description

KHK-IN-1 Hcl is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK.

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Others

References

Pyrimido[5,4-d]pyrimidine-4,8-diamine, N8-(cyclopropylmethyl)-N4-[2-(methylthio)phenyl]-2-(1-piperazinyl)-, hydrochloride (1:1)

N8-(Cyclopropylmethyl)-N4-[2-(methylsulfanyl)phenyl]-2-(1-piperazinyl)pyrimido[5,4-d]pyrimidine-4,8-diamine hydrochloride (1:1)

KHK-IN-1 (hydrochloride)

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Price: $462/10mM*1mLinDMSO