2',4'-Dihydroxy-3',6'-dimethoxychalcone

Modify Date: 2024-01-18 17:39:58

2',4'-Dihydroxy-3',6'-dimethoxychalcone Structure
2',4'-Dihydroxy-3',6'-dimethoxychalcone structure
Common Name 2',4'-Dihydroxy-3',6'-dimethoxychalcone
CAS Number 129724-43-2 Molecular Weight 300.306
Density 1.3±0.1 g/cm3 Boiling Point 556.0±50.0 °C at 760 mmHg
Molecular Formula C17H16O5 Melting Point N/A
MSDS N/A Flash Point 207.3±23.6 °C

 Use of 2',4'-Dihydroxy-3',6'-dimethoxychalcone


2',4'-Dihydroxy-3',6'-dimethoxychalcone is a natural product that can be isolated from Polygonum Lapathifolium. 2',4'-Dihydroxy-3',6'-dimethoxychalcone inhibits the growth of CCRF-CEM leukaemia cells and CEM/ADR5000 cells, with IC50 values of 10.67 and 18.60 μM, respectively[1][2].

 Names

Name (2E)-1-(2,4-Dihydroxy-3,6-dimethoxyphenyl)-3-phenyl-2-propen-1-on e
Synonym More Synonyms

 2',4'-Dihydroxy-3',6'-dimethoxychalcone Biological Activity

Description 2',4'-Dihydroxy-3',6'-dimethoxychalcone is a natural product that can be isolated from Polygonum Lapathifolium. 2',4'-Dihydroxy-3',6'-dimethoxychalcone inhibits the growth of CCRF-CEM leukaemia cells and CEM/ADR5000 cells, with IC50 values of 10.67 and 18.60 μM, respectively[1][2].
Related Catalog
References

[1]. Ahmed M, et al. Isoflavan-4-ol, dihydrochalcone and chalcone derivatives from Polygonum Lapathifolium. Phytochemistry, 1990, 29(6):2009-2011.

[2]. Nkuété AH, et al. Anti-leukemia activity of semi-synthetic phenolic derivatives from Polygonum limbatum Meisn. Chem Cent J. 2015 Jun 24;9:40.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 556.0±50.0 °C at 760 mmHg
Molecular Formula C17H16O5
Molecular Weight 300.306
Flash Point 207.3±23.6 °C
Exact Mass 300.099762
PSA 75.99000
LogP 3.41
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.637

 Safety Information

Hazard Codes Xi
HS Code 2914509090

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

(2Z)-1-(2,4-Dihydroxy-3,6-dimethoxyphenyl)-3-phenyl-2-propen-1-one
2',4'-dihydroxy-3',6'-dimethoxychalcone
2-Propen-1-one, 1-(2,4-dihydroxy-3,6-dimethoxyphenyl)-3-phenyl-, (2Z)-
Benzaldehyde,2,4-dihydroxy-3,5-dimethoxy