Seltorexant

Modify Date: 2025-08-20 11:38:07

Seltorexant structure	Common Name	Seltorexant
	CAS Number	1293281-49-8	Molecular Weight	407.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₂FN₇O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Seltorexant

Seltorexant (JNJ-42847922) is an orally active, high-affinity, and selective OX2R antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R). Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain[1].

Name	Seltorexant

Description	Seltorexant (JNJ-42847922) is an orally active, high-affinity, and selective OX2R antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R). Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Orexin Receptor (OX Receptor) Research Areas >> Neurological Disease
Target	pKi: 8.0 (human OX2R), 8.1 (rat OX2R)[1]
References	[1]. Bonaventure P, et al. Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia. J Pharmacol Exp Ther. 2015 Sep;354(3):471-82.

Molecular Formula	C₂₁H₂₂FN₇O
Molecular Weight	407.44

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Seltorexant
Price: Check
Purity: 98.0%
Delivery: 10 Day
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: Seltorexant
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
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DC Chemicals Limited
China
Product Name: Seltorexant
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Seltorexant

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Seltorexant Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.