cyclotheonamide A
Modify Date: 2025-08-21 17:12:53
cyclotheonamide A structure
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Common Name | cyclotheonamide A | ||
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| CAS Number | 129033-04-1 | Molecular Weight | 731.79800 | |
| Density | 1.44g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C36H45N9O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of cyclotheonamide ACyclotheonamide A is a serine protease inhibitor (cyclic polypeptide), which can be obtained from marine sponges of the genus Theonella. Cyclotheonamide A shows potent inhibitory activity against trypsin (Ki=0.023 µM) and streptokinase (Ki=0.035 µM) and moderate inhibitory activity against human α-thrombin (Ki=0.18 µM). Cyclotheonamide A can be used in study of antithrombotic[1]. |
| Name | N-[(1S)-1-amino-3-[(2S)-2-[(E,6S)-6-amino-2-[(4R)-4-amino-2-(4-hydroxyphenyl)-3-oxo-5-phenylpentanimidoyl]-9-(diaminomethylideneamino)-3-formyl-4,5-dioxonon-2-enoyl]pyrrolidin-1-yl]-3-oxopropyl]formamide |
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| Synonym | More Synonyms |
| Description | Cyclotheonamide A is a serine protease inhibitor (cyclic polypeptide), which can be obtained from marine sponges of the genus Theonella. Cyclotheonamide A shows potent inhibitory activity against trypsin (Ki=0.023 µM) and streptokinase (Ki=0.035 µM) and moderate inhibitory activity against human α-thrombin (Ki=0.18 µM). Cyclotheonamide A can be used in study of antithrombotic[1]. |
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| Related Catalog |
| Density | 1.44g/cm3 |
|---|---|
| Molecular Formula | C36H45N9O8 |
| Molecular Weight | 731.79800 |
| Exact Mass | 731.33900 |
| PSA | 322.29000 |
| LogP | 3.00970 |
| Index of Refraction | 1.677 |
| Cyclotheonamide A |